Home- Research & Innovation- Major Achievements- 2018- Frontier Scientific Breakthroughs

Methylglucosvlation of aromatic amino and phenolic moieties of drug-like bio-svnthons via cormbinatoria biosvnthesis (Prof. Xu Yuquan’s team at the Biotechnology Research Institute , Proceedings of the National Academy of Sciences)

Prof. Xu Yuquan and his team at the Biotechnology Research Institute of CAAS published an article titled "Methyl glucosylation of aromatic amino and phenolic moieties of drug-like bio-synthons via combinatorial biosynthesis" in Proceedings of the National Academy of Sciences. They identified previously undiscovered fungal glucosyltransferase and methyltransferase, and created a synthetic biology platform in which glucosyltransferase and methyltransferase could produce glycosylated polyketides not found in nature, some with increased stability and bioactivity.


实际尺寸-2018-23.jpg

Characterization of Beauveria bassiana glucosyltransferase-methyltransferase module and the bioactivities of methylglucosides

Baidu
map