The Innovation Team of Tobacco Functional Components and Synthetical Utilization from Tobacco Research Institute of CAAS characterized new prenylated indole alkaloids (PIAs) from a tobacco-associated endophytic fungus. PIAs possess high antifungal activity against several plant-pathogenic fungi and remarkable larvicidal activity against the cotton bollworm Helicoverpa armigera with low toxicity, suggesting these compounds have potential to be biopesticides. This study will offer novel lead compounds for the agrochemicals development with independent intellectual property rights.

PIAs characterized from tobaccoassociated endophytic fungus and their agricultural bioactivities